Details of Darunavir Salt (Generic Drug)
Details
Darunavir is a protease inhibitor. Darunavir is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body. Darunavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Darunavir is not a cure for HIV or AIDS. To make sure darunavir is safe for you, tell your doctor if you have liver disease (especially hepatitis or cirrhosis) diabetes a bleeding disorder such as haemophilia high cholesterol or triglycerides or if you are allergic to sulpha drugs. Darunavir can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking darunavir. This medicine should not be given to a child younger than 3 years old.
Typical Uses
Darunavir is used with other HIV medications to help control HIV infection. It helps to decrease the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Darunavir belongs to a class of drugs known as protease inhibitors. Darunavir must be given with certain other medications (such as cobicistat, ritonavir) to increase ("boost") the levels of darunavir. This helps darunavir work better. Darunavir is not a cure for HIV infection.
Side Effects
Darunavir may increase your risk of certain infections or autoimmune disorders by changing the way your immune system works. Symptoms may occur weeks or months after you start treatment with darunavir. Tell your doctor if you have signs of a new infection-fever, night sweats, swollen glands, diarrhoea, weight loss chest pain (especially when you breathe), dry cough, wheezing, feeling short of breath cold sores, sores on your genital or anal area rapid heart rate, feeling anxious or irritable, weakness or prickly feeling, problems with balance or eye movement trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control or swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence, loss of interest in sex.
Drug Interactions
• Darunavir+alfentanil- Darunavir may significantly increase the blood levels of alfentanil. This can increase the risk or severity of side effects such as excessive sedation, respiratory depression, low blood pressure, and irregular heart rhythm. You may need a dose adjustment to safely use both medications.
• Darunavir+brexpiprazole- Darunavir may increase the blood levels of brexpiprazole. This can make you more likely to develop side effects such as drowsiness, seizure, Parkinson-like symptoms, abnormal muscle movements, and low blood pressure. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.
• Darunavir+cyclosporine- Darunavir may increase the blood levels and effects of cyclosporine. You may need a dose adjustment if you have been taking cyclosporine and are starting treatment with darunavir.
• Darunavir+fentanyl- Darunavir may significantly increase the blood levels and effects of fentanyl. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Talk to your doctor if you have any questions or concerns.
• Darunavir+lovastatin- Using darunavir together with lovastatin is not recommended. Combining these medications may significantly increase the blood levels of lovastatin. This can increase the risk of side effects such as liver damage and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysi
Mechanism of action
Darunavir belongs to a class of drugs called protease inhibitors. It binds to and inhibits the activity of protease enzyme of HIV activity, thereby interfering with the multiplication and spread of HIV infection in the body.
Pregnancy Category : C
