Details

Prasugrel helps to prevent platelets in your blood from sticking together and forming a blood clot. An unwanted blood clot can occur with certain heart or blood vessel conditions. Prasugrel is used to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels. Prasugrel increases your risk of bleeding, which can be severe or life-threatening. You should not use prasugrel if you are allergic to it, or if you have any active bleeding such as a stomach ulcer or bleeding in the brain a history of stroke or if you are scheduled to have surgery, especially heart bypass surgery. To make sure prasugrel is safe for you, tell your doctor if you have a stomach ulcer stomach or intestinal bleeding a history of surgery, injury, or medical emergency liver or kidney disease if you also use other medicines to treat or prevent blood clots or if you have ever had a severe allergic reaction to clopidogrel or ticlopidine.

Typical Uses

Prasugrel is used with aspirin by patients with heart disease (recent heart attack, unstable angina) who undergo a certain heart procedure (angioplasty). This medication helps to prevent other serious heart/blood vessel problems (such as heart attacks, strokes, blood clots in stents). It works by blocking platelets from sticking together and prevents them from forming harmful blood clots. This "anti-platelet" effect helps to keep blood flowing smoothly in your body.

Side Effects

Common prasugrel side effects may include a light-headed feeling, like you might pass out any bleeding that will not stop pink or brown urine signs of a serious blood-clotting problem-pale skin, purple spots under your skin or on your mouth, fever, fast heart rate, weakness, stomach pain, trouble breathing, jaundice (yellowing of the skin or eyes) signs of stomach bleeding-bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds or signs of a stroke-sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance. The risk of bleeding is higher in older adults.

Drug Interactions

• Prasugrel+alteplase- Using prasugrel together with alteplase may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
• Prasugrel+bromfenac- Using prasugrel together with bromfenac may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
• Prasugrel+clopidogrel- Using prasugrel together with clopidogrel may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
• Prasugrel+diclofenac- Using prasugrel together with diclofenac may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.
• Prasugrel+ibuprofen- Using prasugrel together with ibuprofen may increase the risk of bleeding, including severe and sometimes fatal haemorrhage. Talk to your doctor if you have any questions or concerns.

Mechanism of action

Prasugrel is belongs to a class of medications called anti-platelet agent. Prasugrel works by preventing platelets (a type of blood cell) to form clots that may cause a heart attack or stroke.

Pregnancy Category : B