Details

Erdotin contains erdosteine, a mucolytic agent, which acts on the phlegm (mucus) in the respiratory tract or airways. Erdosteine is used to treat the symptoms associated with short, severe episodes of worsening of chronic bronchitis. It is also used as an expectorant. Do not take erdosteine if you are hypersensitive (allergic) to erdosteine if you suffer from severe liver failure if you suffer from severe decreased kidney function or if you have a stomach ulcer. The use of erdosteine in pregnant or breastfeeding women is not recommended.

Typical Uses

Mucolytic medicines, such as erdosteine, can be helpful to treat the symptoms of acute flare-ups in chronic bronchitis. Erdosteine works by making mucus (phlegm) less thick and sticky, and therefore easier to cough up.

Side Effects

Some of the side effects of erdosteine include headache cold and difficulty in breathing taste alterations, nausea, vomiting and diarrhoea swelling of the blood vessels below the skin and mucosal tissues due to allergic reaction (angioedema) other skin allergic reactions, such as itching and redness of the skin, oedema and eczema.

Drug Interactions

Presently, there are no known drug interactions for erdosteine.

Mechanism of action

Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.

Pregnancy Category : C