Details

Ebastine is a non sedating anti-histaminic agent. Ebastine is useful for symptomatic relief of allergic conditions including allergic rhinitis and in pruritic skin disorders. Ebastine is not used in hepatic impairment, renal insufficiency, QTC interval prolongation, pregnancy, lactation.

Typical Uses

Ebastine is a non-sedating antihistamine, prescribed for allergic conditions. It blocks histamine action, which reduces allergy symptoms.

Side Effects

Treatment with Ebastine may produce side effects, including headaches, indigestion, drowsy feeling, stomach pain, dryness in the mouth. Other side effects could occur, such as weakness, nosebleeds, difficulty sleeping as well as certain reactions.

Drug Interactions

No data regarding the interactions of Ebastine is available yet.

Mechanism of action

Ebastine is a type of non-sedating second generation antihistamine which is used for allergic disorders. Medical trials showed that it could effectively decrease symptoms of intermittent or seasonal allergic rhinitis and chronic idiopathic urticaria by blocking histamine receptors. Upon ingestion, this medicine undergoes a pharmacological process in which it is converted to its active form carebastine. It then starts to work by means of selectively inhibiting the histamine H1 receptors, and regular dosing will help to consistently retain these effects. Resulting from this, the effects that histamine has on the nasal lining (such as inflammation) are prevented, as the histamine released from the mast cells is unable to work on its receptors.

Pregnancy Category : B