Details

Dorzolamide reduces the amount of fluid in the eye, which decreases pressure inside the eye. Dorzolamide ophthalmic (for the eyes) is used to treat open-angle glaucoma and other causes of high pressure inside the eye. Do not use any other eye medication unless your doctor has prescribed it for you. If you use another eye medication, use it at least 10 minutes before or after using dorzolamide ophthalmic. To make sure you can safely use dorzolamide ophthalmic tell your doctor if you have narrow-angle glaucoma kidney disease or liver disease. Dorzolamide ophthalmic can cause blurred vision.

Typical Uses

Dorzolamide is used to treat high pressure inside the eye due to glaucoma (open angle-type) or other eye diseases (e.g., ocular hypertension). Lowering high pressure inside the eye helps to prevent blindness. This medication works by decreasing the amount of fluid within the eye. It belongs to a class of drugs known as carbonic anhydrase inhibitors.

Side Effects

Although the risk of serious side effects is low when dorzolamide is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream. Stop using dorzolamide ophthalmic and inform your doctor immediately if you have swelling or redness of your eyelids eye redness, pain, discomfort, or sensitivity to light drainage, crusting, or oozing of your eyes or eyelids severe skin reaction: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling or stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).

Drug Interactions

• Dorzolamide+aspirin- Ask your doctor before using dorzolamide ophthalmic together with aspirin. This can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions), or coma. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications.

• Dorzolamide+bismuth subsalicylate- Ask your doctor before using dorzolamide ophthalmic together with bismuth subsalicylate. This can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions), or coma. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications.

• Dorzolamide+diflunisal- Ask your doctor before using dorzolamide ophthalmic together with diflunisal. This can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions), or coma. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications.

• Dorzolamide+salsalate- Ask your doctor before using dorzolamide ophthalmic together with salsalate. This can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions), or coma. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications.

Mechanism of action

Dorzolamide belongs to a class of medications called carbonic anhydrase inhibitors. It works by inhibiting the enzyme carbonic anhydrase thereby causing a reduction in the fluid pressure in the eye.

Pregnancy Category : C