Details

Dexibuprofen is a non-steroidal anti-inflammatory drug, prescribed for moderate to severe pain such as dysmenorrhoea, toothache, osteoarthritis. By blocking COX's action, it reduces the symptoms of pain and inflammation. You should not use dexibuprofen if you have ulcerative colitis, impaired hepatic function, haemorrhagic diathesis, Crohn's disease, severe renal impairment, gastric ulcer, coagulation disorder, bleeding disorders, hypersensitivity to the drug.

Typical Uses

Dexibuprofen is considered as the pharmacologically active enantiomer of racemic Ibuprofen. Like racemic Ibuprofen, Dexibuprofen is a non-steroidal anti-inflammatory drug with analgesic action. Like Ibuprofen, Dexibuprofen acts by inhibiting prostaglandin synthesis.

Side Effects

Some of the side effects of dexibuprofen include gastrointestinal bleeding, heartburn, epigastria pain, dyspepsia, peptic ulcer, nausea, vomiting, diarrhoea, jaundice, hepatitis, rash, thrombocytopenia, visual disturbances, tinnitus, depression, fatigue, headache, dizziness, vertigo.

Drug Interactions

Presently, there are no drug interactions for dexibuprofen available.

Mechanism of action

Dexibuprofen works by blocking the action of a substance in the body called cyclo-oxygenase (COX). Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced by the body in response to injury and certain diseases and conditions. They cause pain, swelling and inflammation. Dexibuprofen blocks the production of these inflammatory prostaglandins and therefore reduces inflammation and pain.

Pregnancy Category : B