Details

Cycloserine is an antibiotic. It prevents tuberculous bacteria from growing in your body. Cycloserine is used to treat tuberculosis (TB). Cycloserine is also sometimes used to treat urinary tract and other types of infections that have not responded to other treatments. Avoid alcohol while taking cycloserine. Alcohol will increase your risk of having a seizure during cycloserine treatment. Alcohol will also increase dizziness and drowsiness. You cannot take cycloserine if you have epilepsy, suffer from depression, have an anxiety disorder, have a psychotic or psychiatric disorder, have kidney disease, or drink alcohol on a daily basis.

Typical Uses

Cycloserine is used with other medications to treat tuberculosis (TB). In some cases, it may also be used to treat urinary tract infections (UTIs). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness. Take cycloserine by mouth with or without food usually twice daily (every 12 hours) or as directed by your doctor.

Side Effects

Some of the side effects of cycloserine include an allergic reaction (difficulty breathing closing of your throat swelling of your lips, tongue, or face or hives) seizures numbness or tingling in your hands or feet a skin rash confusion or abnormal behaviour tremors (shaking) headache drowsiness dizziness difficulty speaking or irritability.

Drug Interactions

• Cycloserine+tramadol- Tramadol may rarely cause seizures, and combining it with other medications that can also cause seizures such as cycloserine may increase that risk. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumour or head trauma.

• Cycloserine+bupropion- Bupropion may rarely cause seizures, and combining it with other medications that can also cause seizures such as cycloserine may increase that risk. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumour or head trauma.

• Cycloserine+iohexol- Before you undergo any imaging procedure where iohexol may be injected directly into the spine let your doctor know if you are currently being treated with cycloserine. Injection of iohexol into the spine can sometimes cause seizures, and the risk may be increased if you are also using other medications that can cause seizures such as cycloserine. The interaction may be more likely if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumour or head trauma.

• Cycloserine+metrizamide- Before you undergo any imaging procedure where metrizamide may be injected directly into the spine let your doctor know if you are currently being treated with cycloserine. Injection of metrizamide into the spine can sometimes cause seizures, and the risk may be increased if you are al

Mechanism of action

Cycloserine is an antibiotic that prevents the infection by inhibiting the essential enzyme required for bacterial growth.

Pregnancy Category : C