Details

Cefazolin is a cephalosporin antibiotic. It works by fighting bacteria in your body. Cefazolin is used to treat many kinds of bacterial infections, including severe or life-threatening forms. To make sure cefazolin is safe for you, tell your doctor if you have kidney disease liver disease a stomach or intestinal disorder such as colitis if you are malnourished or if you are allergic to any type of penicillin.

Typical Uses

Cefazolin is an antibiotic used to treat a wide variety of bacterial infections. It may also be used before and during certain surgeries to help prevent infection. This medication is known as a cephalosporin antibiotic. It works by stopping the growth of bacteria.

Side Effects

Some of the side effects of cefazolin include diarrhoea that is watery or bloody white patches or sores inside your mouth or on your lips fever, swollen glands, rash or itching, joint pain, or general ill feeling seizure (convulsions) liver problems-upper stomach pain, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes) or severe skin reaction-fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Drug Interactions

• Cefazolin+amikacin- Amikacin can sometimes cause kidney damage and using it with a cephalosporin antibiotic like cefazolin may increase that risk. Talk to your doctor if you have any questions or concerns.

• Cefazolin+bumetanide- Cephalosporin antibiotics like cefazolin can occasionally cause kidney problems, and using it with bumetanide may increase that risk. The interaction is more likely to occur when the cephalosporin is given at high dosages by injection into the vein or when it is given to the elderly or individuals with pre-existing kidney function impairment.

• Cefazolin+dicumarol- Using cefazolin together with dicumarol can cause you to bleed more easily. You may need a dose adjustment in addition to testing of your prothrombin time.

• Cefazolin+netilmicin- Netilmicin can sometimes cause kidney damage and using it with a cephalosporin antibiotic like cefazolin may increase that risk. Talk to your doctor if you have any questions or concerns.

Mechanism of action

Cefazolin belongs to group of medicines called cephalosporin antibiotics. It kills the bacteria by interrupting the bacterial cell wall (outer coating of bacteria) formation. As a result, the bacterial cell wall is weakened and ruptured, thereby killing the bacteria.

Pregnancy Category : B