Details

Cabergoline is a dopamine receptor agonist. It works by reducing the amount of prolactin (a hormone) that is released from the pituitary gland. Cabergoline is used to treat a hormone imbalance in which there is too much prolactin in the blood (also called hyperprolactinemia). Before taking cabergoline, tell your doctor if you have liver disease, heart disease, or a breathing disorder. Cabergoline is usually taken twice each week for at least 6 months. Do not take this medication every day unless your doctor tells you to. You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication.

Typical Uses

Cabergoline is used to treat high levels of prolactin hormone in your body. High levels of prolactin in women can cause symptoms such as unwanted breast milk and missed periods and can cause difficulty becoming pregnant. High levels of prolactin in men can cause symptoms such as enlarged breasts and decreased sexual ability/desire. Cabergoline is an ergot medication and works by blocking the release of prolactin from the pituitary gland.

Side Effects

Stop using cabergoline and contact your medical professional immediately if you experience feeling short of breath on exertion chest discomfort, dry cough or hack feeling weak or tired, loss of appetite, rapid weight loss feeling like you might pass out lower back pain urinating less than usual or not at all hot flashes numbness or tingly feeling or swelling in your ankles or feet.

Drug Interactions

• Cabergoline+propoxyphene- Using propoxyphene together with cabergoline may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

• Cabergoline+clarithromycin- Using cabergoline together with clarithromycin is not recommended. Combining these medications may significantly increase the blood levels and effects of cabergoline, which in some cases can lead to excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of rare but serious side effects such as high blood pressure, heart attack, stroke, and gangrene (death of tissues, usually in the arm or leg that may require surgical amputation).

• Cabergoline+erythromycin- Using cabergoline together with erythromycin is not recommended. Combining these medications may significantly increase the blood levels and effects of cabergoline, which in some cases can lead to excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of rare but serious side effects such as high blood pressure, heart attack, stroke, and gangrene (death of tissues, usually in the arm or leg that may require surgical amputation).

• Cabergoline+troleandomycin- Using cabergoline together with troleandomycin is not recommended. Combining these medications may significantly increase the blood levels and effects of cabergoline, which in some cases can lead to excessive narrowing of blood vessels in the body.

Mechanism of action

Cabergoline belongs to class of drugs called dopamine receptor agonists (stimulates dopamine D2 receptor). It mimics the action of dopamine (a chemical naturally released in the brain which transmits messages) to stop release of hormone prolactin.

Pregnancy Category : B