Details of Balofloxacin Salt (Generic Drug)
Details
Balofloxacin is a quinolone antibiotic, prescribed for infective ophthalmitis and sinusitis, chronic bronchitis, acute exacerbation, community-acquired pneumonia, skin infections.
Typical Uses
Balofloxacin is used extensively to treat infective ophthalmitis and sinusitis, chronic bronchitis, acute exacerbation, community-acquired pneumonia, skin infections, Intra-abdominal infections.
Side Effects
Balofloxacin may cause certain side effects including gastrointestinal disturbances, peripheral neuropathy, sensitivity to light, dizziness, fever, abdominal pain, headache, epilepsy and super added fungal infection, irritation when applied locally.
Drug Interactions
Administration of quinolones with antacids containing magnesium interferes with the absorption of quinolones. The agent should not be taken with at once. The concomitant administration of other quinolones with theopyline has elevated serum theophyline has elevated serum theophylline levels. Therefore, the theophylline dosage should be decreased when quinolones is co-administered.
Mechanism of action
The bactericidal action of balofloxacin results from interference with the enzyme DNA gyrase which is needed for the synthesis of bacterial DNA. Balofloxacin is efficacious against Gram-negative bacteria. It also has enhanced activity against Gram-negative bacteria. It also has enhanced activity against gram positive bacteria, Including MRSA and streptococcus pneumoniae.
