Details

Phenoxybenzamine lowers blood pressure. Phenoxybenzamine is used to control blood pressure and reduce sweating in people with pheochromocytoma. Before taking phenoxybenzamine, tell your doctor if you have coronary artery disease, a lung infection, or kidney disease. Avoid drinking alcohol. It can increase drowsiness caused by phenoxybenzamine. If you have coronary artery disease (hardened arteries) a lung infection or kidney disease, you may need a dose adjustment or special tests to safely use phenoxybenzamine.

Typical Uses

Phenoxybenzamine is used to treat high blood pressure and heavy sweating due to a certain tumour of the adrenal glands (pheochromocytoma). Phenoxybenzamine belongs to a class of drugs known as alpha blockers. It works by relaxing and widening blood vessels so that blood can flow more easily. This drug may also be used with other medications to treat certain blood circulation problems (e.g., Reynaud’s syndrome).

Side Effects

Stop using phenoxybenzamine and inform your doctor immediately if you have severe dizziness or if you feel like you might pass out. Other side effects of phenoxybenzamine may include stuffy nose mild dizziness or drowsiness blurred vision trouble having an orgasm upset stomach or tired feeling.

Drug Interactions

• Phenoxybenzamine+tizanidine- Tizanidine and phenoxybenzamine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, light-headedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption.

Mechanism of action

Phenoxybenzamine belongs to a class of drugs called alpha blockers. It acts on nerve endings of the blood vessels which causes muscle relaxation, thereby lowering blood pressure.

Pregnancy Category : C