Details

Griseofulvin is an antifungal medication that fights infections caused by fungus. Griseofulvin is used to treat infections such as ringworm, athlete's foot, jock itch, and fungal infections of the scalp, fingernails, or toenails. To make sure griseofulvin is safe for you, tell your doctor if you have liver disease lupus an allergy to penicillin or if you take a blood thinner such as warfarin. Taking griseofulvin during the first trimester of pregnancy can harm the unborn baby. Griseofulvin may make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking griseofulvin. Griseofulvin should not be given to a child younger than 2 years old.

Typical Uses

Griseofulvin is used to treat fungal infections of the skin, hair, and nails that do not respond to creams/lotions. Clearing such infections will get rid of symptoms such as itching, red/peeling/scaly skin, and discoloured nails. This medication works by stopping the growth of fungi. It does not treat infections due to bacteria or yeast.

Side Effects

Common side effects of griseofulvin include fever, chills, flu symptoms, white patches or sores inside your mouth or on your lips confusion, trouble with daily activities liver problems-nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-coloured stools, jaundice (yellowing of the skin or eyes) lupus-like syndrome-joint pain or swelling with fever, swollen glands, muscle aches, chest pain, vomiting, unusual thoughts or behaviour, and patchy skin colour or severe skin reaction-fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Drug Interactions

• Griseofulvin+medroxyprogesterone- Talk to your doctor before using medroxyprogesterone together with griseofulvin. Combining these medications may decrease the blood levels and effects of medroxyprogesterone. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. Because use of griseofulvin has been associated with birth defects, it is particularly important that you do not become pregnant during treatment.
• Griseofulvin+levonorgestrel- Talk to your doctor before using levonorgestrel together with griseofulvin. Combining these medications may decrease the blood levels and effects of levonorgestrel. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. Because use of griseofulvin has been associated with birth defects, it is particularly important that you do not become pregnant during treatment.
• Griseofulvin+ranolazine- Using ranolazine together with griseofulvin is not recommended. Combining these medications may significantly reduce the blood levels of ranolazine, which may make the medication ineffective or less effective. Talk to your doctor if you have any questions or concerns.
• Griseofulvin+norethindrone- Talk to your doctor before using norethindrone together with griseofulvin. Combining these medications may decrease the blood levels and effects of norethindrone. If you are using low-dose oral contraceptives, you may have an increased risk of breakthrough bleeding and unintended pregnancy. Because use of griseofulvin has been a

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Mechanism of action

Griseofulvin belongs to the group of medicines called antifungals. It reduces infection caused by fungus by killing the fungus and also makes the skin resistant to fungal infection.

Pregnancy Category : C